amice Utrecht

Translational Neuroimaging (TNi) is a multidisciplinary group including physicists, engineers, (bio)technicians, neuroscientists and medical trainees. We aim to enable detailed characterization of neuronal and vascular (dys)function in the brain and to assess promising treatments for cerebrovascular diseases. We focus on developing and applying (high-field) MRI technology, which encompasses hardware, data acquisition and analysis methods, and biophysical and computational modeling. Our preclinical laboratory is equipped with two animal MR systems at 7 T (30-cm horizontal bore) and 9.4 T (20-cm horizontal bore). We integrate MRI with other methods and measures such as MR spectroscopy, optical imaging, ultrasound, electrocorticography, neurostimulation, behavioral testing and histology. Our translational research stretches from basic science to clinical trials and is embedded in the strategic research programs Brain and Circulatory Health of the UMC Utrecht, with many connections to various scientists and clinicians.